co2

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Learn Better, 4 Gifts, and How Breathing Can Actually Change the World

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Today is a special edition of The Breathing 411.

Because today is 4/11.

It’s also World Breathing Day.

And it also happens to be my 35th birthday (to celebrate, I did one breath per minute for 35 minutes this morning <— maybe I’ll make it a new tradition 🙏).

To honor the occasion, there are 4 Free Gifts in Thought #3 below.

Thank you from the bottom of my heart for reading.

With love,

Nick

 

🎧 Listen Instead of Reading 🎧

If you enjoy listening, you can subscribe to the audio version on Spotify, Apple Podcasts, and Audible so you don’t even have to look at the email 😊

 

4 Thoughts



1. How Breathing Can Actually Change the World, in 3 Super Practical Steps

  • Step 1: Tape your mouth at night.

  • Step 2: Breathe nasally 90-95% of the day.

  • Step 3: Forget about the rest, and use your newfound energy from Steps 1 & 2 to help you do whatever you were put on this planet to do.

2. ANB Significantly Enhances Learning and Retention of New Motor Skills

“Our results thus uncover for the first time the remarkable facilitatory effects of simple breathing practices on complex functions such as motor memory”

- Deep Breathing Practice Facilitates Retention of Newly Learned Motor Skills

This 2016 study on alternate nostril breathing (ANB), published in Nature Scientific Reports, genuinely blew my mind. (See full review in Thought #3.)

Here’s what they did:

  • Participants learned a new motor skill.

  • A control group rested for 30 minutes.

  • A breathing group did 30-min of ANB.

  • Then, both groups were tested on the skill they had learned.

  • Both groups were also tested again 24-hours later.

The results showed that the ANB group significantly (it was almost ridiculous) improved the learning and retention of that skill:

  • They were significantly better at the 30-min mark.

  • They were significantly better at the 24-hour mark.

One 30-minute breathing session. One day of improved learning and retention.

3. Science 411s, Book 411s, and The Breath is Life Learning Center (4 free gifts)

To celebrate World Breathing Day, here are four gifts.

Science 411s: 4 Fundamentals, 1 Big Takeaway, and 1 Practical Application

  • Free Science 411: Deep Breathing Practice Facilitates Retention of Newly Learned Motor Skills (the paper from Thought #2 above)

  • Free Science 411: Heart Rate Variability Biofeedback Improves Emotional and Physical Health and Performance: A Systematic Review and Meta Analysis

Book 411s: 4 Thoughts, 1 Quote, and 1 Idea That Will Change Your Life

  • Free Book 411: The Happiness Track: How To Apply The Science Of Happiness To Accelerate Your Success

  • Free Book 411: The Art of Impossible: A Peak Performance Primer

You can read, listen, or download them as PDFs here.

I hope you enjoy them!

4. Why We Breathe: Chemically and Spiritually

“Our drive to breathe is regulated by the medulla oblongata … When pH decreases (becomes more acidic due to the increase in CO2), chemoreceptors in the medulla send out a signal for the body to breathe. This means that our carbon dioxide levels have to rise to a sufficiently high level for our brain and body to know that it is time to take the next breath.”

- Inna Khazan, Ph.D.

It’s the perfect day to review why we breathe. So there’s the technical reason.

But breathing is a lot more than just gases. As Michael J Stephen, MD, tells us,

“That oxygen, life, and lungs all came into our world in relatively close succession is no coincidence. Only with oxygen and some means of extracting it are all things possible—thinking, moving, eating, speaking, and loving. Life and the breath are synonymous.”

So beyond chemistry, we ultimately breathe to live—to think, to move, to love. Breathing is, after all, what makes “all things possible.”


 
 
 

1 QUOTE

“It was ecstasy, it was sweet, air soughing in and all my little alveoli singing away with joy and oxygen-energy coursing through every space and particle of me.”

- Keri Hulme

 
 
 
 

1 ANSWER

Category: Body Chemical Composition

Answer: This gas is the most abundant element in the human body by mass.

…

(Cue the Jeopardy! music.)

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Question: What is oxygen?

In good breath,

Nick Heath, T1D, PhD
“Breathing is the compound interest of health & wellness.”

P.S. I’m only 35, I have my whole life ahead of me

 
 
 

* An asterisk by a quote indicates that I listened to this book on Audible. Therefore, the quotation might not be correct, but is my best attempt at reproducing the punctuation based on the narrator’s pace, tone, and pauses.

Sign Up For The Breathing 411

Each Monday, I curate and synthesize information from scientific journals, books, articles, and podcasts to share 4 thoughts, 1 quote, and 1 answer (like "Jeopardy!") related to breathing. It’s a fun way to learn something new each week.

 
 

Use it or Lose it + Eating and Breathing

 

Happy Monday! I hope you all have a great week ahead.

Here are 4 thoughts, 1 quote, and 1 answer for you to consider this week.

 
 
 
 

4 THOUGHTS

1. The Nose: Use it or Lose it

"Machines: use it and lose it; organisms: use it or lose it."

- Frano Barovic, Antifragile

I had to get a new computer recently. My Macbook Pro gave me 7 great years, but it was time to move on. I decided to switch to a Macbook Air. I thought, "air is my favorite subject; I should get a computer called an Air." I’m that weird : )

So when I was recently re-reading Antifragile, the quote above (buried in a footnote) popped off the page. We expect machines like my computer to break over time: use it and lose it. But with our body, it’s the opposite: use it or lose it.

This is especially true for one particular organ, the nose. Here’s how James Nestor puts it:

"For noses clogged, you need to find a way of unclogging it. You can do that by breathing more through your nose because it's really a use-it-or-lose-it organ. The more you breathe through it, the more you're going to be able to breathe through it." - NPR Interview

We learned some tricks for unblocking your nose a couple weeks ago. But the ultimate nose-unblocking exercise is to simply use it or lose it.

2. Thinkr Review of Breath

"Though it seems as simple as inhaling and exhaling, the act of breathing is an overlooked artform that can do much more than just sustain life." - Thinkr Review of Breath

Speaking of James Nestor, here’s an excellent summary of his book Breath that I recently came across. It requires an email to sign-up, but you can unsubscribe afterward…although I’ve actually enjoyed the emails they’ve sent since.

If you haven’t read Breath or just need a refresher, this is a nice summary from a company with no vested interest in "breathing."

3. Using Breathing Science to Change the World

Changing our breathing is one of the simplest thing we can do to improve our health. Tiny changes, like switching to nose breathing 24/7, can dramatically impact our health and wellness. That’s why it is great to see researchers using breathing in practical ways that could really change the world.

For example, imagine having a web browser add-on that, without you knowing it, alters your breathing to be more relaxed and rhythmic (rather than e-mail-apnea). That’s what "Breathing Edges" aims to do:

Toward Breathing Edges: A Prototype Respiration Entrainment System for Browser-based Computing Tasks

Or how about audio tracks that slow down your breathing while driving:

Just Breathe: In-Car Interventions for Guided Slow Breathing

Or audio tracks that speed up your breathing to keep you awake when you’re driving late at night:

Breath Booster!: Exploring In-Car, Fast-Paced Breathing Interventions to Enhance Driver Arousal State

It’s awesome to see things like this being developed, and it’ll be exciting to see what the next few years of research and application bring.

4. Can Eating Affect Your Breathing?

"One is able to compare the different fuel sources in this regard by examining the respiratory quotient (RQ), the ratio of carbon dioxide produced per unit of oxygen consumed in the production of energy…The RQ for carbohydrate is 1.0; for fats, it is 0.7; and for protein, it is 0.8." - Respiratory Physiology, A Clinical Approach

The "respiratory quotient" shows how much CO2 is produced per unit of oxygen consumed for energy production. For example, 30% less CO2 is generated when fat is used for energy compared to carbohydrates.

Thus, what you eat might affect how you breathe.

This might help explain why some endurance athletes prefer fueling with fat vs. carbs. Or why we can often hold our breath longer in the morning when we are fasted and using fat for energy. Less CO2 production means less breathlessness and extended breath holds.

This also explains why I start breathing heavily when I splurge on cheesecake : )

We often think about how breathing can help with digestion and post-meal blood sugar spikes. But I guess we should not forget the relationship goes both ways.

 
 
 
 

1 QUOTE

"Since we cannot know all that there is to be known about anything, we ought to know a little about everything."

- Blaise Pascal

Thanks to new 411 reader T. V. for inspiring this quote.

 
 
 
 

1 ANSWER

This section of the newsletter was inspired by my favorite TV show of all time, Jeopardy! With the passing of Alex Trebek yesterday morning, it feels impossible to make an answer about breathing this week. Instead, let’s honor the legacy of this great man.

Answer: From 1984 to 2020, Alex Trebek hosted more than this many episodes of Jeopardy!, earning him spot in the Guinness Book of World Records.

…

(Cue the Jeopardy! music.)

…

Question: What is 8,200?

We love you, Alex.

 
 

Exciting News: A New Breathing Gas Discovered

 

Happy Monday. There was a breakthrough in breathing research over the past few weeks: A new breathing gas has been discovered. I hope the extra hour of sleep you got this weekend will help this exciting news sink in even deeper.

OK, let’s get to it. Here are 4 thoughts, 1 quote, and 1 answer for you to think about as we begin November.

 
 
 
 

4 THOUGHTS

1. A New Breathing Gas Discovered

"Thus, H2S [hydrogen sulfide] produced by CBS surely has a crucial role in maintaining eupneic-pattern respiration."

- Nature, Communications Biology

Hydrogen sulfide. It’s toxic, and it’s what gives rotten eggs their rotten smell. It also helps maintain our breathing.

A study published in Nature: Communications Biology on October 16, 2020, found that a small amount of hydrogen sulfide is critical to maintaining normal breathing. It does this through modification of the neural connections in the region of the brain that controls breathing.

When hydrogen sulfide production was stopped in rats, normal breathing turned to gasping, implying that it is vital to maintaining rhythmic breathing.

From a practical perspective, I’m not sure what this means yet. At a minimum, breathing now appears to be a four-gas system: oxygen, carbon dioxide, nitric oxide, and hydrogen sulfide.

We’ve found ways to breathe to optimize the first three. However, it’s not yet clear if the way we breathe (or do anything else, for that matter) can influence hydrogen sulfide.

In any case, as a fellow breathing nerd, I hope you find this as fascinating and humbling as I did. Here’s to the joy of never-ending learning.

P.S. Here’s a short summary of these findings from ScienceDaily.

2. The Single Most Important Part of the Breath

"Interestingly, Törnberg et al. recently showed that more NO is released from the nasal passages during nasal inhalation compared with exhalation." - Lundberg et al. (2008)

Here is yet another reason why inhaling through your nose might be the single most important part of breathing: nitric oxide (NO) production is much greater during inhalation than exhalation.

Here’s the finding from the paper mentioned above: "There was a marked flow dependency of nasal NO output, with the highest levels observed during inhalation at flows similar to those seen during normal breathing." - Törnberg et al. (2002)

In hindsight, this makes complete sense. NO helps protect our lungs from inhaled pathogens and it redistributes blood flow in the lungs. So, of course our bodies would maximize it on the inhale. But it wasn’t until I read these two papers that it made sense to me.

"The obvious is that which is never seen until someone expresses it simply.” - Kahlil Gibran

3. What Focusing on the Breath Does to Your Brain

"Conversely, it may be possible to reduce fear and anxiety by slowing down our breath." - Greater Good, UC Berkeley

Here is a quick-reading article, packed full of excellent information, from The Greater Good Science Center at UC Berkeley. Anytime you see a headline like "Managing stress: Is it all in the breath?" you know it’s going to be a good read. Enjoy!

4. Sleep Scientists Call for the Elimination of Daylight Saving Time

"It is, therefore, the position of the American Academy of Sleep Medicine that these seasonal time changes should be abolished in favor of a fixed, national, year-round standard time."

- Journal of Clinical Sleep Medicine

I hope you all enjoyed the extra hour of sleep you got this weekend. The world’s leading sleep scientists say your body will function better, and they suggest we keep it this way (Standard Time) forever.

The above article is pretty short. But if you’re interested, here’s an even more concise summary, along with a rather impressive list of organizations that support the permanent change to Standard Time.

Because nasal breathing at night changed my life, I am endlessly fascinated with sleep. So I hope we all enjoy the next few months of better sleep and better optimization of our body's wake-light cycles.

 
 
 
 

1 QUOTE

“A mind that is stretched by a new experience can never go back to its old dimensions.”

- Oliver Wendell Holmes

 
 
 
 

1 ANSWER

Answer: Average walking speed (~2-4 mph) is also around the average speed of this physiological function.

…

(Cue the Jeopardy music.)

…

Question: What is blood flow?

In good breath,
Nick

P.S. New life in a new city.

 
 

Is This Stuff Really in Textbooks? And A New Nose-Opening Method

 

Hello, and happy Monday. Here are 4 thoughts, 1 quote, and 1 answer for you to consider as we wrap up October.

 
 
 
 

4 THOUGHTS

1. Is this Stuff Really in Textbooks?

Carbon dioxide (CO2) and the Bohr effect have motivated almost all the interest in breathing for health and performance.

CO2 is said to loosen the bond between oxygen and hemoglobin, allowing more efficient release into the tissues (the Bohr effect). Thus, counterintuitively, by breathing less (retaining more CO2), we actually get more oxygen.

It is often stated that this is just basic (but underappreciated) physiology that is in all the medical textbooks. Luckily, I find joy in reading medical books I don’t fully understand : ) Here’s what I have found:

- “Hemoglobin’s affinity for oxygen is also influenced by pH, carbon dioxide concentration, and body temperature…it releases it more readily under conditions of…increased carbon dioxide concentration." - Essentials of Pathophysiology, pg. 534

- “The shift of the curve to the right may be seen as a compensation that results in greater release of oxygen to the tissues…Temperature affects the relationship (increases in body temperature shift the curve to the right), as do carbon dioxide." - Respiratory Physiology, A Clinical Approach, pg. 110

- “Most of the effect of PCO2, which is known as the Bohr effect, can be attributed to its action on H+ concentration. A rightward shift means more unloading of O2 at a given PO2 in a tissue capillary." - Respiratory Physiology, The Essentials, pg. 91

So yes, this is basic physiology. It’s nothing new. But knowledge is only potential energy. What we’re doing is applying this knowledge in a simple way. Breathe less, get more.

2. A New Nose-Unblocking Exercise

Patrick McKeown’s nose unblocking exercise is phenomenal. It’s simple, and you feel it immediately. However, no one knows precisely how it works. My hypothesis is that it’s primarily due to nasal nitric oxide (but have no way of testing this, except on myself).

It just so happens that last week we discovered a way of breathing that increases nasal nitric oxide (nose in - mouth out). It also just so happens that I got a terribly stuffy nose during that same time.

So, here was my N=1 test. If the unblocking exercise works due to NO, it would stand that performing nasal-in, mouth-out breathing would help clear my nose.

So here’s what I did. I inhaled through my nose, pinched my nose, slowly exhaled through my mouth as long as I could comfortably, and repeated. And, lo and behold, it helped.

However, it took much longer than Patrick’s method (about 2 minutes for me). And, it wasn’t nearly as dramatic. Each breath only opened it slightly more. Conversely, in Patrick’s version, you go from blocked to open almost instantly.

What does this mean? Well, nothing, really. There are many factors to consider. But it *might* be suggesting that NO is, in fact, the “unblocking” mechanism.

So, here’s my request: If you get a stuffy nose this cold season, give it a try and let me know if it does anything for you. N=1 means nothing statistically, but it’s better than nothing practically.

3. For the Practice or For the Results? Why Not Both?

"How do you best move toward mastery? To put it simply, you practice diligently, but you practice primarily for the sake of the practice itself." - Robert Greene, Mastery

Why do you practice breathing? For the practice itself, or for the outcome?

What I love about breathing is that it can be both. In fact, you automatically take care of both, regardless of which one you are focusing on. It’s health and mastery, wrapped in our body’s most important function.

4. Woo-Woo or Wu-Wei?

"It refers to the dynamic, effortless, and unselfconscious state of mind of a person who is optimally active and effective."

- Edward Slingerland, Trying Not to Try

Wu-Wei literally means "effortless action." If it didn’t sound so much like "woo-woo," it might be the perfect definition of ideal breathing.

We train our breathing so that we don’t have to think about it. We train our breathing to achieve this state of effortless yet highly effective action.

 
 
 
 

1 QUOTE

“It’s not enough to understand; you’ve got to do something.”

- Sandra Day O’Connor

 
 
 
 

1 ANSWER

Answer: On one breath, the world record for this movement is 81.6 meters.

…

(Cue the Jeopardy music.)

…

Question: What is underwater walking?

(P.S. The video is pretty amazing. Watch out Laird.)

In good breath,
Nick

P.S. Very Scary.